Ascorbate oxidation is a prerequisite for its transport into rat liver microsomal vesicles.

نویسندگان

  • M Csala
  • V Mile
  • A Benedetti
  • J Mandl
  • G Bánhegyi
چکیده

Oxidation and uptake of ascorbate show similar time courses in rat liver microsomal vesicles: a rapid burst phase is followed by a slower process. Inhibitors of ascorbate oxidation (proadifen, econazole or quercetin) also effectively decreased the uptake of ascorbate. The results show that dehydroascorbate is the transport form of ascorbate at the membrane of the endoplasmic reticulum.

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عنوان ژورنال:
  • The Biochemical journal

دوره 349 Pt 2  شماره 

صفحات  -

تاریخ انتشار 2000